CPRD Researcher - £40,451 p.a. + benefits

KNO06D Requisition #

We would like to reassure all applicants that we are continuing to recruit through these challenging circumstances. For any vacancies advertised we are proceeding with Video Interviews where possible and are facilitating remote homeworking for all positions where possible. Should you have any queries on the current recruitment process at the MHRA please contact careers@mhra.gov.uk.

We currently have a great opportunity for two CPRD Researchers within the CPRD Division to work full time on an 18 month fixed term contract.

The Medicines and Healthcare products Regulatory Agency enhance and improve the health of millions of people every day through the effective regulation of medicines and medical devices, underpinned by science and research.

Clinical Practice Research Datalink (CPRD), jointly funded by the agency and the National Institute for Health Research (NIHR), is the UK’s preeminent research service providing anonymised NHS data for retrospective and prospective research. CPRD services are designed to maximise the way anonymised NHS clinical data can be used to safeguard public health and improve the efficiency of clinical research. For more than 30 years, data provided by CPRD have supported a range of drug safety and epidemiological studies that have impacted on health care and resulted in over 2500 peer-reviewed publications. The UK is in a unique global position to use patient records in novel ways for patient recruitment, clinical trials management and follow up. In addition to supporting high quality observational research, CPRD is developing world leading services based on real world data to support clinical trials and intervention studies.


The CPRD Researcher will apply their epidemiological, statistical, data management and data analysis expertise to further public health research. Specifically, the post holder will undertake internal development, collaborative and commissioned research, provide scientific input to the review of research applications submitted to the MHRA Independent Scientific Advisory Committee (ISAC) to use CPRD data for research, and create and deliver study specific datasets for external clients. The role will also involve input into the development and application of best practice that contribute to the maintenance of CPRD as a centre of excellence for observational data research and services.

Key responsibilities:

  • Execute and deliver collaborative and commissioned research studies including the development of study protocols and practical interpretation of the aims and objectives of the project
  • Support the scientific functions of the ISAC through the application of epidemiological knowledge to formulate reviews for research proposing use of CPRD data
  • Interpret and operationalise research protocols to produce extraction specifications for epidemiological studies across a range of therapeutic and/or disease areas, including linkage to other health and health-related datasets.
  • Contribute to the development and timely roll out of a range of new and enhanced observational products and research services, such as innovative methodologies, standard and non-standard data linkages, algorithms and analytical tools
  • Engage with senior members of CPRD, potential and existing CPRD clients, and internal stakeholders. Liaise with members of CPRD staff across teams to apply the highest levels of governance and assurance

The successful candidate will have the following:

  • Excellent verbal and written communication skills including the ability to communicate in a clear, succinct and engaging manner
  • Excellent organisational skills with a proven ability to undertake and deliver multiple projects on time
  • In depth understanding of epidemiological principles and statistical concepts
  • Familiarity with research using primary care data and other health related data sources
  • Sound knowledge of the challenges involved in using health data in public health research
  • A degree in Epidemiology, Medical Statistics, Health Economics, Public Health or equivalent related qualification
  • Proven ability in conducting epidemiological research using large complex longitudinal datasets
  • Competence in STATA and/or R is essential


If you would like to know more about this role, please click on the Job Description and Person Specification.


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Please ensure all application questions are completed in full; your application may not be considered if any responses are left blank. Please note that applications are blind, and your CV will not be accessible to Hiring Managers during the reviewal of applications.

Closing date: 24th November 2020


If you need assistance applying for this role or have any other questions please contact careers@mhra.gov.uk

Candidates will be subject to UK immigration requirements as well as Civil Service nationality rules.

Our process requires that you apply through our careers site, where you will be asked to complete your application and answer some competency based questions. Applicants are assessed on whether they meet any mandatory requirements as well as the necessary skills and experience for the role. Applicants are scored on their competency answers so please ensure you have read these thoroughly and allow sufficient time. You can view the competencies for this role in the job description.

In accordance with the Civil Service Commissioners’ Recruitment Principles our recruitment and selection processes are underpinned by the requirement of selection for appointment on the basis of merit by a fair and open competition. If you feel your application has not been treated in accordance with the Recruitment Principles and you wish to make a complaint, you should firstly contact Mira Mepa, Head of Recruitment and Operations, Mira.Mepa@mhra.gov.uk.

If you are not satisfied with the response you receive, you can contact the Civil Service Commission at: civilservicecommission.independent.gov.uk


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